Revision [3037]
Last edited on 2010-09-07 14:08:24 by LeonoreGolayAdditions:
For years medicine has used implants to improve or reestablish functions in the human body. These implants remain in the patient's body either for life or for a longer time. Smart implants go beyond what is used now and may detect poor bone ingrowth, infection, subsidence or dislocation once an implant is in place. One can imagine the step further where truly smart implant would have greater capabilities such as the ability to remotely turn on and off, collect data and be reprogrammed.
Deletions:
Revision [2931]
Edited on 2010-07-13 13:05:48 by LeonoreGolayAdditions:
For years medicine has used implants to improve or reestablish functions in the human body. These implants remain in the patient�s body either for life or for a longer time. Smart implants go beyond what is used now and may detect poor bone ingrowth, infection, subsidence or dislocation once an implant is in place. One can imagine the step further where truly smart implant would have greater capabilities such as the ability to remotely turn on and off, collect data and be reprogrammed.
The ""Theken eDisc�"" is the first artificial disc to incorporate microelectronics � namely a flip-chip flex circuit,� says Styblo. �The three piezoelectric force transducers in the eDisc measure dynamic forces, linear responses, and transient motions that are of clinical interest,� he says. The device, which uses in vivo telemetry, has been tested on body phantom, cadaveric, and non-human primate tests. **[[[http://ilo.osu.edu/2009/09/01/valtronic-technologies-manufacturing-miniaturized-sensors-and-devices/ 4]]]**
Parvizi and colleagues at the Rothman Institute in Philadelphia are developing a hip prosthesis with a smart anti-infective surface. �We have put smart bombs on the surface � that will recognize the infective organisms in the vicinity and then will cleave or will deliver the antibiotic to the organisms,� he said. Antibiotics start working when they recognize an organism following a drop in pH of the peri-prosthetic chemical environment. **[[[http://www.orthosupersite.com/view.asp?rid=28657 5]]]**
A patient has received an investigational, full artificial knee replacement that can wirelessly report digital, 3 dimensional torque and force data back to computers. This second generation implant provides a wealth of new information: twisting, bending, compressive, and shearing loads across the human knee � all reported dynamically in vivo.
The ""Theken eDisc�"" is the first artificial disc to incorporate microelectronics � namely a flip-chip flex circuit,� says Styblo. �The three piezoelectric force transducers in the eDisc measure dynamic forces, linear responses, and transient motions that are of clinical interest,� he says. The device, which uses in vivo telemetry, has been tested on body phantom, cadaveric, and non-human primate tests. **[[[http://ilo.osu.edu/2009/09/01/valtronic-technologies-manufacturing-miniaturized-sensors-and-devices/ 4]]]**
Parvizi and colleagues at the Rothman Institute in Philadelphia are developing a hip prosthesis with a smart anti-infective surface. �We have put smart bombs on the surface � that will recognize the infective organisms in the vicinity and then will cleave or will deliver the antibiotic to the organisms,� he said. Antibiotics start working when they recognize an organism following a drop in pH of the peri-prosthetic chemical environment. **[[[http://www.orthosupersite.com/view.asp?rid=28657 5]]]**
A patient has received an investigational, full artificial knee replacement that can wirelessly report digital, 3 dimensional torque and force data back to computers. This second generation implant provides a wealth of new information: twisting, bending, compressive, and shearing loads across the human knee � all reported dynamically in vivo.
Deletions:
The ""Theken eDisc™"" is the first artificial disc to incorporate microelectronics – namely a flip-chip flex circuit,” says Styblo. “The three piezoelectric force transducers in the eDisc measure dynamic forces, linear responses, and transient motions that are of clinical interest,” he says. The device, which uses in vivo telemetry, has been tested on body phantom, cadaveric, and non-human primate tests. **[[[http://ilo.osu.edu/2009/09/01/valtronic-technologies-manufacturing-miniaturized-sensors-and-devices/ 4]]]**
Parvizi and colleagues at the Rothman Institute in Philadelphia are developing a hip prosthesis with a smart anti-infective surface. “We have put smart bombs on the surface … that will recognize the infective organisms in the vicinity and then will cleave or will deliver the antibiotic to the organisms,” he said. Antibiotics start working when they recognize an organism following a drop in pH of the peri-prosthetic chemical environment. **[[[http://www.orthosupersite.com/view.asp?rid=28657 5]]]**
A patient has received an investigational, full artificial knee replacement that can wirelessly report digital, 3 dimensional torque and force data back to computers. This second generation implant provides a wealth of new information: twisting, bending, compressive, and shearing loads across the human knee – all reported dynamically in vivo.
Revision [2716]
Edited on 2010-03-18 17:24:57 by LeonoreGolayAdditions:
===Special Topics===
**[[Energy Energy]]**
**[[SensorNetwork Wireless Network Sensor]]**
**[[CarbonNanotube Carbon Nanotubes]]**
**[[MicroFluidics Micro Fluidics]]**
**[[GreenComputing Green Computing]]**
**[[Energy Energy]]**
**[[SensorNetwork Wireless Network Sensor]]**
**[[CarbonNanotube Carbon Nanotubes]]**
**[[MicroFluidics Micro Fluidics]]**
**[[GreenComputing Green Computing]]**
Revision [2689]
Edited on 2010-03-18 16:45:09 by LeonoreGolayAdditions:
@@======SMART & BIO-IMPLANTS======@@
===={{color text="NEWS" c="#000000"}}""""====
==== ""MEMSCAP"" & OrthoChip: Wireless Pressure Sensor to Measure Spinal Disk====
==== "" Bilkent"" University: Bio-implantable passive on-chip RF-MEMS strain sensing resonators for orthopaedic applications====
==== ""Valtronic"" Technologies: Manufacturing Miniaturized Sensors and Devices====
====""Rothman Institute"": Smart implants to provide biofeedback, measure joint loads, detect infection====
====""MicroStrain"" & ""DePuy Orthopedics"": wireless sensors measure 3-D force inside an implant====
====""Fraunhofer Institute"": Intelligent hip-joint prosthesis====
===={{color text="COMPANIES & INSTITUTIONS" c="#000000"}}""""====
===={{color text="REFERENCES" c="#000000"}}""""====
===={{color text="SEE ALSO" c="#000000"}}""""====
===={{color text="NEWS" c="#000000"}}""""====
==== ""MEMSCAP"" & OrthoChip: Wireless Pressure Sensor to Measure Spinal Disk====
==== "" Bilkent"" University: Bio-implantable passive on-chip RF-MEMS strain sensing resonators for orthopaedic applications====
==== ""Valtronic"" Technologies: Manufacturing Miniaturized Sensors and Devices====
====""Rothman Institute"": Smart implants to provide biofeedback, measure joint loads, detect infection====
====""MicroStrain"" & ""DePuy Orthopedics"": wireless sensors measure 3-D force inside an implant====
====""Fraunhofer Institute"": Intelligent hip-joint prosthesis====
===={{color text="COMPANIES & INSTITUTIONS" c="#000000"}}""""====
===={{color text="REFERENCES" c="#000000"}}""""====
===={{color text="SEE ALSO" c="#000000"}}""""====
Deletions:
===={{color text="NEWS" c="#000000"}}""""====
==== ""MEMSCAP"" & OrthoChip: Wireless Pressure Sensor to Measure Spinal Disk====
==== "" Bilkent"" University: Bio-implantable passive on-chip RF-MEMS strain sensing resonators for orthopaedic applications====
==== ""Valtronic"" Technologies: Manufacturing Miniaturized Sensors and Devices====
====""Rothman Institute"": Smart implants to provide biofeedback, measure joint loads, detect infection====
====""MicroStrain"" & ""DePuy Orthopedics"": wireless sensors measure 3-D force inside an implant====
====""Fraunhofer Institute"": Intelligent hip-joint prosthesis====
===={{color text="COMPANIES & INSTITUTIONS" c="#000000"}}""""====
===={{color text="REFERENCES" c="#000000"}}""""====
===={{color text="SEE ALSO" c="#000000"}}""""====
Revision [2600]
Edited on 2010-03-09 20:08:24 by NanoTeraWikiAdminAdditions:
For years medicine has used implants to improve or reestablish functions in the human body. These implants remain in the patient’s body either for life or for a longer time. Smart implants go beyond what is used now and may detect poor bone ingrowth, infection, subsidence or dislocation once an implant is in place. One can imagine the step further where truly smart implant would have greater capabilities such as the ability to remotely turn on and off, collect data and be reprogrammed.
==== ""MEMSCAP"" & OrthoChip: Wireless Pressure Sensor to Measure Spinal Disk====
**{[[http://www.memscap.com/en_profiler.html MEMSCAP]] / Dr. Jean Michel KARAM CEO ; OrthoMEMS / Douglas Lee, CEO }**
The combined experience and technologies of MEMSCAP and OrthoMEMS, the companies report, will enable the development and commercialization of the OrthoChip, a miniature, batteryless, wireless pressure sensor that will provide an objective measurement of spinal disk pressures. The OrthoChip is designed to detect clear-cut pressure differences between normal and mechanically unstable spinal segments and to communicate the results telemetrically to a readout unit. This new capability is expected to significantly alter indications for surgery and nonsurgical treatments, the companies report, adding that no other technology, existing or emerging, provides this advantage. **[[[http://www.edn.com/article/CA6659471.html 1]]]**, **[[[http://www.reuters.com/article/pressRelease/idUS118350+09-Jun-2009+BW20090609 2]]]**
==== "" Bilkent"" University: Bio-implantable passive on-chip RF-MEMS strain sensing resonators for orthopaedic applications====
**{ Bilkent University - [[http://www.nano.org.tr/ Institute of Materials Science and Nanotechnology]] / Hilmi Volkan Demir}**
We have designed novel, bio-implantable, passive, on-chip, RF-MEMS strain sensors that rely on the resonance frequency shift with mechanical deformation. For this purpose, we modeled, fabricated and experimentally characterized two on-chip sensors with high quality factors for in vivo implantation. **[[[http://www.iop.org/EJ/abstract/0960-1317/18/11/115017/ 3]]]**
==== ""Valtronic"" Technologies: Manufacturing Miniaturized Sensors and Devices====
**{[[http://www.valtronictechnologies.com/ Valtronic]] / Donald Styblo, VP of Technology}**
Electronics are being placed into skeletal implants which measure and record data. This data can be read by the physician through remotely powered unidirectional telemetry within the implant.
The ""Theken eDisc™"" is the first artificial disc to incorporate microelectronics – namely a flip-chip flex circuit,” says Styblo. “The three piezoelectric force transducers in the eDisc measure dynamic forces, linear responses, and transient motions that are of clinical interest,” he says. The device, which uses in vivo telemetry, has been tested on body phantom, cadaveric, and non-human primate tests. **[[[http://ilo.osu.edu/2009/09/01/valtronic-technologies-manufacturing-miniaturized-sensors-and-devices/ 4]]]**
====""Rothman Institute"": Smart implants to provide biofeedback, measure joint loads, detect infection====
**{[[http://www.rothmaninstitute.com Rothman Institute in Philadelphia]] / Dr. Parvizi, MD}**-
Parvizi and colleagues at the Rothman Institute in Philadelphia are developing a hip prosthesis with a smart anti-infective surface. “We have put smart bombs on the surface … that will recognize the infective organisms in the vicinity and then will cleave or will deliver the antibiotic to the organisms,” he said. Antibiotics start working when they recognize an organism following a drop in pH of the peri-prosthetic chemical environment. **[[[http://www.orthosupersite.com/view.asp?rid=28657 5]]]**
====""MicroStrain"" & ""DePuy Orthopedics"": wireless sensors measure 3-D force inside an implant====
**{[[www.microstrain.com MicroStrain]] for the Sensors / [[www.depuyorthopedics.com DePuy Orthopedics]] for the implants}**
A patient has received an investigational, full artificial knee replacement that can wirelessly report digital, 3 dimensional torque and force data back to computers. This second generation implant provides a wealth of new information: twisting, bending, compressive, and shearing loads across the human knee – all reported dynamically in vivo.
These data will provide key inputs for new designs, techniques for implantation, and actual use of knee replacements. **[[[http://www.microstrain.com/media_center/Orthopaedic_getting_smarter.pdf 6]]]**
====""Fraunhofer Institute"": Intelligent hip-joint prosthesis====
**{[[http://www.ipms.fraunhofer.de/en/ Fraunhofer Institute for Photonic Microsystems]]}**
A problem with implanted artificial hip-joints is the control of the firm anchorage of the prosthesis in the bone. With the transponder system a micro system has been developed that also keeps track of the growth of the thigh bone to the artificial limb. **[[[http://www.ipms.fhg.de/common/products/LIF/Med/implant-e.pdf 7]]]**
===={{color text="COMPANIES & INSTITUTIONS" c="#000000"}}""""====
===Companies===
""MEMSCAP""
""Valtronic""
""Theken eDisk""
===Institutions===
""Rothman Institute in Philadelphia""
""Fraunhofer Institute"" for Photonic Microsystems
""Bilkent University"" - Institute of Materials Science and Nanotechnology
""DePuy Orthopaedics""
""MicroStrain""
===={{color text="REFERENCES" c="#000000"}}""""====
1. http://www.edn.com/article/CA6659471.html
2. http://www.reuters.com/article/pressRelease/idUS118350+09-Jun-2009+BW20090609
3. http://www.iop.org/EJ/abstract/0960-1317/18/11/115017/
4. http://ilo.osu.edu/2009/09/01/valtronic-technologies-manufacturing-miniaturized-sensors-and-devices/
5. http://www.orthosupersite.com/view.asp?rid=28657
6. http://www.microstrain.com/media_center/Orthopaedic_getting_smarter.pdf
7. http://www.ipms.fhg.de/common/products/LIF/Med/implant-e.pdf
===={{color text="SEE ALSO" c="#000000"}}""""====
**[[http://www.nano-tera.ch/topdownbottomup/index.html Nano-Tera Top-Down Bottom-Up]]**
**[[BodyMonitoring Body Health Monitoring]]**
**[[HomePage NanoTeraWiki HomePage]]**
[[CategoryWiki]]
==== ""MEMSCAP"" & OrthoChip: Wireless Pressure Sensor to Measure Spinal Disk====
**{[[http://www.memscap.com/en_profiler.html MEMSCAP]] / Dr. Jean Michel KARAM CEO ; OrthoMEMS / Douglas Lee, CEO }**
The combined experience and technologies of MEMSCAP and OrthoMEMS, the companies report, will enable the development and commercialization of the OrthoChip, a miniature, batteryless, wireless pressure sensor that will provide an objective measurement of spinal disk pressures. The OrthoChip is designed to detect clear-cut pressure differences between normal and mechanically unstable spinal segments and to communicate the results telemetrically to a readout unit. This new capability is expected to significantly alter indications for surgery and nonsurgical treatments, the companies report, adding that no other technology, existing or emerging, provides this advantage. **[[[http://www.edn.com/article/CA6659471.html 1]]]**, **[[[http://www.reuters.com/article/pressRelease/idUS118350+09-Jun-2009+BW20090609 2]]]**
==== "" Bilkent"" University: Bio-implantable passive on-chip RF-MEMS strain sensing resonators for orthopaedic applications====
**{ Bilkent University - [[http://www.nano.org.tr/ Institute of Materials Science and Nanotechnology]] / Hilmi Volkan Demir}**
We have designed novel, bio-implantable, passive, on-chip, RF-MEMS strain sensors that rely on the resonance frequency shift with mechanical deformation. For this purpose, we modeled, fabricated and experimentally characterized two on-chip sensors with high quality factors for in vivo implantation. **[[[http://www.iop.org/EJ/abstract/0960-1317/18/11/115017/ 3]]]**
==== ""Valtronic"" Technologies: Manufacturing Miniaturized Sensors and Devices====
**{[[http://www.valtronictechnologies.com/ Valtronic]] / Donald Styblo, VP of Technology}**
Electronics are being placed into skeletal implants which measure and record data. This data can be read by the physician through remotely powered unidirectional telemetry within the implant.
The ""Theken eDisc™"" is the first artificial disc to incorporate microelectronics – namely a flip-chip flex circuit,” says Styblo. “The three piezoelectric force transducers in the eDisc measure dynamic forces, linear responses, and transient motions that are of clinical interest,” he says. The device, which uses in vivo telemetry, has been tested on body phantom, cadaveric, and non-human primate tests. **[[[http://ilo.osu.edu/2009/09/01/valtronic-technologies-manufacturing-miniaturized-sensors-and-devices/ 4]]]**
====""Rothman Institute"": Smart implants to provide biofeedback, measure joint loads, detect infection====
**{[[http://www.rothmaninstitute.com Rothman Institute in Philadelphia]] / Dr. Parvizi, MD}**-
Parvizi and colleagues at the Rothman Institute in Philadelphia are developing a hip prosthesis with a smart anti-infective surface. “We have put smart bombs on the surface … that will recognize the infective organisms in the vicinity and then will cleave or will deliver the antibiotic to the organisms,” he said. Antibiotics start working when they recognize an organism following a drop in pH of the peri-prosthetic chemical environment. **[[[http://www.orthosupersite.com/view.asp?rid=28657 5]]]**
====""MicroStrain"" & ""DePuy Orthopedics"": wireless sensors measure 3-D force inside an implant====
**{[[www.microstrain.com MicroStrain]] for the Sensors / [[www.depuyorthopedics.com DePuy Orthopedics]] for the implants}**
A patient has received an investigational, full artificial knee replacement that can wirelessly report digital, 3 dimensional torque and force data back to computers. This second generation implant provides a wealth of new information: twisting, bending, compressive, and shearing loads across the human knee – all reported dynamically in vivo.
These data will provide key inputs for new designs, techniques for implantation, and actual use of knee replacements. **[[[http://www.microstrain.com/media_center/Orthopaedic_getting_smarter.pdf 6]]]**
====""Fraunhofer Institute"": Intelligent hip-joint prosthesis====
**{[[http://www.ipms.fraunhofer.de/en/ Fraunhofer Institute for Photonic Microsystems]]}**
A problem with implanted artificial hip-joints is the control of the firm anchorage of the prosthesis in the bone. With the transponder system a micro system has been developed that also keeps track of the growth of the thigh bone to the artificial limb. **[[[http://www.ipms.fhg.de/common/products/LIF/Med/implant-e.pdf 7]]]**
===={{color text="COMPANIES & INSTITUTIONS" c="#000000"}}""""====
===Companies===
""MEMSCAP""
""Valtronic""
""Theken eDisk""
===Institutions===
""Rothman Institute in Philadelphia""
""Fraunhofer Institute"" for Photonic Microsystems
""Bilkent University"" - Institute of Materials Science and Nanotechnology
""DePuy Orthopaedics""
""MicroStrain""
===={{color text="REFERENCES" c="#000000"}}""""====
1. http://www.edn.com/article/CA6659471.html
2. http://www.reuters.com/article/pressRelease/idUS118350+09-Jun-2009+BW20090609
3. http://www.iop.org/EJ/abstract/0960-1317/18/11/115017/
4. http://ilo.osu.edu/2009/09/01/valtronic-technologies-manufacturing-miniaturized-sensors-and-devices/
5. http://www.orthosupersite.com/view.asp?rid=28657
6. http://www.microstrain.com/media_center/Orthopaedic_getting_smarter.pdf
7. http://www.ipms.fhg.de/common/products/LIF/Med/implant-e.pdf
===={{color text="SEE ALSO" c="#000000"}}""""====
**[[http://www.nano-tera.ch/topdownbottomup/index.html Nano-Tera Top-Down Bottom-Up]]**
**[[BodyMonitoring Body Health Monitoring]]**
**[[HomePage NanoTeraWiki HomePage]]**
[[CategoryWiki]]
Deletions:
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**[[http://www.nano-tera.ch/nanoterawiki/BioImplants#News News]]
===={{color text="NEWS" c="#000000"}}""""====
===={{color text="NEWS" c="#000000"}}""""====
Deletions:
[[http://www.nano-tera.ch/nanoterawiki/BioImplants#News News]]
===={{color text="INTRODUCTION" c="#000000"}}""""====
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@@======{{color text=" SMART & BIO-IMPLANTS" c="#953735"}}======@@
----
===={{color text="CONTENT" c="#000000"}}====
**[[http://www.nano-tera.ch/nanoterawiki/BioImplants#Intro Introduction]]
[[http://www.nano-tera.ch/nanoterawiki/BioImplants#Comp Companies & Institutions]]
[[http://www.nano-tera.ch/nanoterawiki/BioImplants#News News]]
[[http://www.nano-tera.ch/nanoterawiki/BioImplants#Ref References]]
[[http://www.nano-tera.ch/nanoterawiki/BioImplants#See See Also]]
**
----
===={{color text="INTRODUCTION" c="#000000"}}""""====
----
===={{color text="CONTENT" c="#000000"}}====
**[[http://www.nano-tera.ch/nanoterawiki/BioImplants#Intro Introduction]]
[[http://www.nano-tera.ch/nanoterawiki/BioImplants#Comp Companies & Institutions]]
[[http://www.nano-tera.ch/nanoterawiki/BioImplants#News News]]
[[http://www.nano-tera.ch/nanoterawiki/BioImplants#Ref References]]
[[http://www.nano-tera.ch/nanoterawiki/BioImplants#See See Also]]
**
----
===={{color text="INTRODUCTION" c="#000000"}}""""====
Deletions:
----====={{color text="INTRODUCTION" c="#000000"}}=====
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----====={{color text="INTRODUCTION" c="#000000"}}=====
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====={{color text="INTRODUCTION" c="#000000"}}=====
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